Ann Intern Med 1985 Oct;103(4):539-41

Thrombolytic therapy for inferior vena cava thrombosis in paroxysmal nocturnal hemoglobinuria 

Sholar PW, Bell WR

Abstract
Two patients with paroxysmal nocturnal hemoglobinuria had increasing abdominal
girth and ascites. The Budd-Chiari syndrome or inferior vena cava thrombosis was
shown by angiography. After thrombolytic therapy, both patients improved, and
thrombolysis was shown by radiography. Neither patient had induction of
hemolysis secondary to these agents. These studies suggest that both
streptokinase and urokinase are safe and effective in the treatment of
intra-abdominal venous thromboses associated with paroxysmal nocturnal
hemoglobinuria